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recombinant rabbit anti human cd163 monoclonal antibody  (Huabio Inc)
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anti cd163 primary antibody  (OriGene)
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Fimepinostat Corrects Loss of Merlin-related Cytokine Expression and Decreases MCP-1 Secretion. ( A , B ). Cytokine array analysis of 10 patient-derived vestibular schwannoma (VS) samples showed IL-6, IL-8, and MCP-1 as the most highly expressed in VS cells alone and VS–monocyte cocultures. ( C ). Addition of monocytes to VS cultures significantly increased secretion of MCP-2, MCP-3, macrophage inflammatory protein-1β (MIP-1b), and osteopontin (OPN) (* p < 0.05). ( D , E ). Immunocytochemistry for <t>CD163+</t> M2 macrophages (green) and S100B+ VS cells (red), nuclei are stained in blue. ( F ). Cytokine array analysis of HS11 (WT) and HS02 (MD) untreated and treated with 100 nM fimepinostat for 24 h (Mean ± SD, *** p < 0.0005 and **** p < 0.0001). ( G ). MCP-1 ELISA of HS11 and HS02 cells untreated and treated with 100 nM fimepinostat at 6, 16, and 24 h (Mean ± SD, ** p < 0.005 and *** p < 0.0005).
Anti Cd163 Primary Antibody, supplied by OriGene, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
anti cd163 primary antibody - by Bioz Stars, 2026-07
94/100 stars
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rabbit monoclonal anti cd163 antibody  (Cell Signaling Technology Inc)
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Fimepinostat Corrects Loss of Merlin-related Cytokine Expression and Decreases MCP-1 Secretion. ( A , B ). Cytokine array analysis of 10 patient-derived vestibular schwannoma (VS) samples showed IL-6, IL-8, and MCP-1 as the most highly expressed in VS cells alone and VS–monocyte cocultures. ( C ). Addition of monocytes to VS cultures significantly increased secretion of MCP-2, MCP-3, macrophage inflammatory protein-1β (MIP-1b), and osteopontin (OPN) (* p < 0.05). ( D , E ). Immunocytochemistry for <t>CD163+</t> M2 macrophages (green) and S100B+ VS cells (red), nuclei are stained in blue. ( F ). Cytokine array analysis of HS11 (WT) and HS02 (MD) untreated and treated with 100 nM fimepinostat for 24 h (Mean ± SD, *** p < 0.0005 and **** p < 0.0001). ( G ). MCP-1 ELISA of HS11 and HS02 cells untreated and treated with 100 nM fimepinostat at 6, 16, and 24 h (Mean ± SD, ** p < 0.005 and *** p < 0.0005).
Rabbit Monoclonal Anti Cd163 Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rabbit monoclonal anti cd163 antibody - by Bioz Stars, 2026-07
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scavenger receptor cysteine rich type 1 protein m130  (OriGene)
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Fimepinostat Corrects Loss of Merlin-related Cytokine Expression and Decreases MCP-1 Secretion. ( A , B ). Cytokine array analysis of 10 patient-derived vestibular schwannoma (VS) samples showed IL-6, IL-8, and MCP-1 as the most highly expressed in VS cells alone and VS–monocyte cocultures. ( C ). Addition of monocytes to VS cultures significantly increased secretion of MCP-2, MCP-3, macrophage inflammatory protein-1β (MIP-1b), and osteopontin (OPN) (* p < 0.05). ( D , E ). Immunocytochemistry for <t>CD163+</t> M2 macrophages (green) and S100B+ VS cells (red), nuclei are stained in blue. ( F ). Cytokine array analysis of HS11 (WT) and HS02 (MD) untreated and treated with 100 nM fimepinostat for 24 h (Mean ± SD, *** p < 0.0005 and **** p < 0.0001). ( G ). MCP-1 ELISA of HS11 and HS02 cells untreated and treated with 100 nM fimepinostat at 6, 16, and 24 h (Mean ± SD, ** p < 0.005 and *** p < 0.0005).
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scavenger receptor cysteine rich type 1 protein m130 - by Bioz Stars, 2026-07
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anti cd163  (Bioss)
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Fimepinostat Corrects Loss of Merlin-related Cytokine Expression and Decreases MCP-1 Secretion. ( A , B ). Cytokine array analysis of 10 patient-derived vestibular schwannoma (VS) samples showed IL-6, IL-8, and MCP-1 as the most highly expressed in VS cells alone and VS–monocyte cocultures. ( C ). Addition of monocytes to VS cultures significantly increased secretion of MCP-2, MCP-3, macrophage inflammatory protein-1β (MIP-1b), and osteopontin (OPN) (* p < 0.05). ( D , E ). Immunocytochemistry for <t>CD163+</t> M2 macrophages (green) and S100B+ VS cells (red), nuclei are stained in blue. ( F ). Cytokine array analysis of HS11 (WT) and HS02 (MD) untreated and treated with 100 nM fimepinostat for 24 h (Mean ± SD, *** p < 0.0005 and **** p < 0.0001). ( G ). MCP-1 ELISA of HS11 and HS02 cells untreated and treated with 100 nM fimepinostat at 6, 16, and 24 h (Mean ± SD, ** p < 0.005 and *** p < 0.0005).
Anti Cd163, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
anti cd163 - by Bioz Stars, 2026-07
94/100 stars
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cd163  (OriGene)
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OriGene cd163
Fimepinostat Corrects Loss of Merlin-related Cytokine Expression and Decreases MCP-1 Secretion. ( A , B ). Cytokine array analysis of 10 patient-derived vestibular schwannoma (VS) samples showed IL-6, IL-8, and MCP-1 as the most highly expressed in VS cells alone and VS–monocyte cocultures. ( C ). Addition of monocytes to VS cultures significantly increased secretion of MCP-2, MCP-3, macrophage inflammatory protein-1β (MIP-1b), and osteopontin (OPN) (* p < 0.05). ( D , E ). Immunocytochemistry for <t>CD163+</t> M2 macrophages (green) and S100B+ VS cells (red), nuclei are stained in blue. ( F ). Cytokine array analysis of HS11 (WT) and HS02 (MD) untreated and treated with 100 nM fimepinostat for 24 h (Mean ± SD, *** p < 0.0005 and **** p < 0.0001). ( G ). MCP-1 ELISA of HS11 and HS02 cells untreated and treated with 100 nM fimepinostat at 6, 16, and 24 h (Mean ± SD, ** p < 0.005 and *** p < 0.0005).
Cd163, supplied by OriGene, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Fimepinostat Corrects Loss of Merlin-related Cytokine Expression and Decreases MCP-1 Secretion. ( A , B ). Cytokine array analysis of 10 patient-derived vestibular schwannoma (VS) samples showed IL-6, IL-8, and MCP-1 as the most highly expressed in VS cells alone and VS–monocyte cocultures. ( C ). Addition of monocytes to VS cultures significantly increased secretion of MCP-2, MCP-3, macrophage inflammatory protein-1β (MIP-1b), and osteopontin (OPN) (* p < 0.05). ( D , E ). Immunocytochemistry for CD163+ M2 macrophages (green) and S100B+ VS cells (red), nuclei are stained in blue. ( F ). Cytokine array analysis of HS11 (WT) and HS02 (MD) untreated and treated with 100 nM fimepinostat for 24 h (Mean ± SD, *** p < 0.0005 and **** p < 0.0001). ( G ). MCP-1 ELISA of HS11 and HS02 cells untreated and treated with 100 nM fimepinostat at 6, 16, and 24 h (Mean ± SD, ** p < 0.005 and *** p < 0.0005).

Journal: International Journal of Molecular Sciences

Article Title: Fimepinostat Promotes Apoptosis and Decreases Cytokine Secretion in NF2 -Related Human Schwannoma Cells

doi: 10.3390/ijms27062636

Figure Lengend Snippet: Fimepinostat Corrects Loss of Merlin-related Cytokine Expression and Decreases MCP-1 Secretion. ( A , B ). Cytokine array analysis of 10 patient-derived vestibular schwannoma (VS) samples showed IL-6, IL-8, and MCP-1 as the most highly expressed in VS cells alone and VS–monocyte cocultures. ( C ). Addition of monocytes to VS cultures significantly increased secretion of MCP-2, MCP-3, macrophage inflammatory protein-1β (MIP-1b), and osteopontin (OPN) (* p < 0.05). ( D , E ). Immunocytochemistry for CD163+ M2 macrophages (green) and S100B+ VS cells (red), nuclei are stained in blue. ( F ). Cytokine array analysis of HS11 (WT) and HS02 (MD) untreated and treated with 100 nM fimepinostat for 24 h (Mean ± SD, *** p < 0.0005 and **** p < 0.0001). ( G ). MCP-1 ELISA of HS11 and HS02 cells untreated and treated with 100 nM fimepinostat at 6, 16, and 24 h (Mean ± SD, ** p < 0.005 and *** p < 0.0005).

Article Snippet: Immunocytochemistry was performed with anti-CD163 primary antibody (1:100, OriGene, TA506383), S100B (1:100, Abcam, ab52642), AlexaFluor-488- and 594-conjugated secondary antibodies (1:500; Invitrogen), and DAPI nuclear stain, as previously described [ ].

Techniques: Expressing, Derivative Assay, Immunocytochemistry, Staining, Enzyme-linked Immunosorbent Assay